Regulation of Kidney Function -
- The functioning of the kidneys is efficiently monitored and regulated by hormonal feedback mechanisms involving the hypothalamus, JGA and to a certain extent, the heart.
Control by Juxtaglomerular Apparatus:
- The JGA plays a complex regulatory role.
- A fall in glomerular blood flow/glomerular blood pressure/GFR can activate the JG cells to release renin which converts angiotensinogen in the blood to angiotensin I and further to angiotensin II.
- Angiotensin II, being a powerful vasoconstrictor, increases the glomerular blood pressure and thereby GFR.
- Angiotensin II also activates the adrenal cortex to release Aldosterone.
- Aldosterone causes reabsorption of Na+ and water from the distal parts of the tubule.
- This also leads to an increase in blood pressure and GFR.
- This complex mechanism is generally known as the Renin-Angiotensin-Aldosterone mechanism.
Angiotensin is secreted by liver. Hence the correct option is liver
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