Desmosomes connect
Cell to ECM
Cell to Cell membrane
Cell to cell
Cell to fibres
Adhering junctions: These act like cement to keep neighbouring cells together. These are of three types
(a). Zonula adherens: These are dense plaque-like structure towards the cytoplasmic side of each plasma membrane from which fine microfilaments are extended into the cytoplasm.
(b). Desmosomes: These are also plaque-like thicker and stronger junctions with microfilaments of keratin protein. These microfilaments are called tonofibrils. This anchor the cells.
(c). Hemidesmosome: These are similar to desmosomes, but the thickening of the cell membrane is seen on one side only. These join epithelial cells to the basal lamina.
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Desmosomes are the adherens junctions that connect cell to cell.