Erythrocytes or Red Blood Cells -
- These are the cells which give blood its characteristic red colour.
- The red colour is due to the presence of an iron-containing compound called haemoglobin.
- Mammalian erythrocytes are enucleated and biconcave.
- The biconcave shape is important as it provides a large surface-to-volume ratio to facilitate gas exchange.
- The nucleus and other organelles are lost during development and maturation of RBC.
- The number of RBC per microlitre of blood is about 5 million in men and 4.5 million in women.
- Formation of RBCs is called erythropoiesis. It takes place in the liver and spleen during embryonic stages. From birth onwards, it takes place in bone marrow.
- A term erythrocytopenia is used for denoting the decreased number of erythrocytes.
- Similarly, the term erythrocytosis or polycythemia is used to denote an increased number of erythrocytes.
- The average lifespan of human erythrocytes is of 120 days.
- RBCs are important for the transport of oxygen and carbon dioxide, maintenance of pH in blood etc.
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Formation of RBCs is called erythropoiesis. It takes place in the liver and spleen during embryonic stages. From birth onwards, it takes place in bone marrow.
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