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  •  Physiologically urea is produced by the action of an enzyme   Option: 1 Argi

 Physiologically urea is produced by the action of an enzyme 

 

Option: 1

Arginase

 


Option: 2

Urease

 


Option: 3

Uricase

 


Option: 4

None of these

 


Answers (1)

best_answer

 

 

Formation of Urea - Krebs-Henseleit Cycle -

  • Ammonia is converted to urea in the hepatocytes of the liver in five steps via urea cycle- in the mitochondria (first 2 steps) and cytosol (last 3 steps). 
  • The urea then travels through the bloodstream to the kidney and is excreted in the urine.
  • The urea cycle was discovered by Hans Krebs (who also discovered Citric acid or Krebs cycle) and his student associate Kurt Henseleit in 1932. 
  • Five enzymes take part in the formation of urea. Out of these the first four are found in all cells. But the last enzyme arginase is found only in the liver cells thus assuring the formation of final product urea only in the liver despite the formation of arginine in other tissues.

 

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Arginine is broken down by arginase to urea and ornithine. Hence, the correct option is arginase

Posted by

Anam Khan

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