If a double stranded DNA has 20% of cytosine, what will be the percentage of adenine in it ?
20 %
30 %
40 %
60 %
Types of Nitrogenous bases -
There are two types:
1. Purines
2. Pyrimidines
- wherein
Purines include Adenine and Guanine and Pyrimidines include Cytosine Uracil and Thymine.
According to Chargaff’s rule, the amount of adenine is always equal to that of thymine and the amount of guanine is always equal to that of cytosine, i.e. A= T and G=C. Also, the purines and pyrimidines are always in equal amounts, i.e A+G =T+C. Now, given dsDNA has 20% cytosine and hence guanine will be also 20%.
So, A+T must be 60%. Therefore, percentage of adenine would be 60/2=30%.