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  • The disease sickle-cell anaemia is caused by the substitution of (i)__________ by (ii)___________ at the (iii)___________ position of (iv)____________ globin chain of haemoglobin molecule. <

The disease sickle-cell anaemia is caused by the substitution of (i)__________ by (ii)___________ at the (iii)___________ position of (iv)____________ globin chain of haemoglobin molecule.

Which of the following correctly fills the blanks in the above statement ?

Option: 1

(i) valine, (ii) glutamic acid , (iii) sixth , (iv) beta


Option: 2

(i) glutamic acid , (ii) valine , (iii) sixth , (iv) beta


Option: 3

(i) glutamic acid , (ii) valine , (iii) fifth , (iv) beta


Option: 4

(i) valine, (ii) glutamic acid , (iii) fifth , (iv) beta


Answers (1)

best_answer

As we learnt ,

Example of point mutation -

A classical example of point mutation is a change of single base pair in the gene for beta globin chain that results in the change of amino acid residue glutamate to valine.  

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chirag

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