Isomers and Stereoisomers
Anomers:
- When a molecule such as glucose converts to a cyclic form, it generates a new chiral centre at C-1.
- The carbon atom that generates the new chiral centre (C-1) is called the anomeric carbon.
- Anomers are the epimers that differ in configuration only at the anomeric carbon.
- For example, α-D-glucose and β-D-glucose are anomers.
- The α form has the anomeric -OH group at C-1 on the opposite side of the ring from the CH2OH group at C-5. The β form has the anomeric -OH group on the same side as the CH2OH group.

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The functional group on the glucose is -CHO (aldehyde) while on fructose is -COR (ketone).
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