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Oxygen Transport and Oxygen Dissociation Curve -
- Blood is the medium of transport for
and
.
- About 97 percent of
is transported by RBCs in the blood.
- The remaining 3 percent of
is carried in a dissolved state through the plasma.
- Haemoglobin is a red coloured iron-containing pigment present in the RBCs.
can bind with haemoglobin in a reversible manner to form oxyhaemoglobin. This is called O2-Hb association.
- Each haemoglobin molecule can carry a maximum of four molecules of
.
- Binding of oxygen with haemoglobin is primarily related to the partial pressure of
.
is high in alveoli so association occurs while at the tissues, the
decreases which cause dissociation of oxygen.
- The partial pressure of
, hydrogen ion concentration and temperature are the other factors which can interfere with this binding.
- A sigmoid curve is obtained when the percentage saturation of haemoglobin with
is plotted against the
.
- This curve is called the Oxygen dissociation curve.
- This curve is highly useful in studying the effect of factors like
2, H+ concentration, etc, on the binding of
100 with haemoglobin.
- Every 100 ml of oxygenated blood can deliver around 5 ml of
to the tissues under normal physiological conditions.
-
Each haemoglobin molecule can carry a maximum of four molecules of
. Hence, the correct option is 4
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