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  • When percentage saturation of haemoglobin with  is plotted against the <img alt="pO_{2}" src="https://lea

When percentage saturation of haemoglobin with O_{2} is plotted against the pO_{2}, a ________ curve is obtained. Choose the correct option to fill in the blank.

 

Option: 1

Hyperbola

 


Option: 2

Straight

 


Option: 3

Sigmoid

 


Option: 4

None of the above

 


Answers (1)

best_answer

 

 

Oxygen Transport and Oxygen Dissociation Curve -

  • Blood is the medium of transport for O_{_{2}} and CO_{_{2}}. 
  • About 97 percent of O_{_{2}} is transported by RBCs in the blood. 
  • The remaining 3 percent of O_{_{2}} is carried in a dissolved state through the plasma. 
  • Haemoglobin is a red coloured iron-containing pigment present in the RBCs. 
  • O_{_{2}} can bind with haemoglobin in a reversible manner to form oxyhaemoglobin. This is called O2-Hb association.
  • Each haemoglobin molecule can carry a maximum of four molecules of O_{_{2}}.
  • Binding of oxygen with haemoglobin is primarily related to the partial pressure of O_{_{2}}.
  • pO_{_{2}} is high in alveoli so association occurs while at the tissues, the pO_{_{2}} decreases which cause dissociation of oxygen.
  • The partial pressure of CO_{_{2}}, hydrogen ion concentration and temperature are the other factors which can interfere with this binding. 
  • A sigmoid curve is obtained when the percentage saturation of haemoglobin with O_{_{2}} is plotted against the pO_{_{2}}. 
  • This curve is called the Oxygen dissociation curve.
  • This curve is highly useful in studying the effect of factors like pCO_{_{2}} 2, H+ concentration, etc, on the binding of O_{_{2}} 100 with haemoglobin.

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Hence, A sigmoid curve is obtained when percentage saturation of haemoglobin with O_{2} is plotted against the pO_{2}.

Posted by

Ritika Jonwal

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