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Which of the following is least likely to be involved in establishing the 3-D folding of most proteins?

Option: 1

Hydrogen bonds


Option: 2

Electrostatic interaction


Option: 3

Hydrophobic interaction


Option: 4

Ester bonds


Answers (1)

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Structure of Proteins - Tertiary & Quaternary Structure

  • The tertiary structure of a protein is its unique three-dimensional structure. 
  • It occurs due to the following interactions:

                          -Hydrophobic Interactions
                          -Van Der Waals Interactions
                          -Disulfide Bridges
                          -H-bonds and Ionic Bonds

  • Some proteins are formed from several polypeptides, also known as subunits, and the interaction of these subunits forms the quaternary structure.
  • For example, Hemoglobin protein has two α and two β polypeptides together with four heme groups.
  • Weak interactions between the subunits help to stabilize the overall structure.

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It occurs due to the following interactions: Hydrophobic Interactions, Van Der Waals Interactions, Disulfide Bridges, H-bonds and Ionic Bonds.

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