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  • (a) Explain linkage and recombination as put forth by T.H. Morgan based on his observations with Drosophila melanogaster crossing experiment. (b) Write the basis on which Alfred Sturtevent explained gene mapping.  

(a) Explain linkage and recombination as put forth by T.H. Morgan based on his observations with Drosophila melanogaster crossing experiment.

(b) Write the basis on which Alfred Sturtevent explained gene mapping.

 

 

 

 
 
 
 
 

Answers (1)

(a) Morgan carried out several dihybrid crosses in drosphila to study genes that were sex linked. Example- Mendel hybridised yellow - bodied, white eyed females to brown bodied, red eyed males and intercrossed their F1 progeny. He observed that the two genes did not segregate independently and the F2 ratio deviated from 9:3:3:1 ratio.

Morgan and his group saw that the proportion of parental gene combination were much higer than non - parental ones.

When the genes were situated on the same chromosomes. Morgan attributed this due to the physical association or linkage of two genes and coined the term linkage to describe this physical association of genes on a chromosomes and the term recombination to describe the generation of non - parental gene combinations.

They also found that even when genes were grouped on the same chromosomes, some genes were very tightly linked (showed very low recombination) while others were loosely linked (showed higher recombination).

(b) Alfred Sturtvent used the frequency of recombination between gene pairs on the same chromosomes as a measure of distance between genes and 'mapped' their positions on the chromosomes.

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Priyanka Kumari

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