Name the disorder in humans with the following karyotype :
(a) 22 pairs of autosomes + XO
(b) 22 pairs of autosomes + 21st chromosome + XY
a) Turner’s syndrome
Such females are sterile as ovaries are rudimentary besides other features including lack of other secondary sexual characters.
b) Down syndrome
The affected individual is short-statured with a small round head, furrowed tongue and partially open mouth. Palm is broad with characteristic palm crease. Physical, psychomotor and mental development is retarded.