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  • Differentiate between rough and smooth endoplasmic reticulum. How is endoplasmic reticulum important for membrane biogenesis?

Differentiate between rough and smooth endoplasmic reticulum. How is endoplasmic reticulum important for membrane biogenesis?

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Differences between Rough Endoplasmic Reticulum & Smooth Endoplasmic Reticulum.

Rough Endoplasmic Reticulum

Smooth Endoplasmic Reticulum

The rough Endoplasmic Reticulum has ribosomes on its surface.

Smooth Endoplasmic Reticulum lacks ribosomes and this is the reason they are known as smooth endoplasmic reticulum.

Rough Endoplasmic Reticulum is in vesicular and tubular form.

Smooth Endoplasmic Reticulum has flattened sacs known as cisternae.

Rough Endoplasmic Reticulum is present more around the nucleus therefore deep in the cytoplasm.

Smooth Endoplasmic Reticulum is present closer to the cell membrane than the nucleus so these are not deep in the cell.

The rough Endoplasmic Reticulum's main function is to synthesize proteins and enzymes.

The smooth Endoplasmic Reticulum is involved in the synthesis of lipids glycogen and steroids.

Role of smooth endoplasmic reticulum and rough endoplasmic reticulum: In cell membrane, mainly made up of lipids (40-45%) and proteins (50-60%), the endoplasmic reticulum with ribosomes is actively involved in the synthesis of proteins and enzymes. Smooth endoplasmic reticulum is involved in the synthesis of lipids which are the key constituents of cell membranes. This is how rough endoplasmic reticulum and smooth endoplasmic reticulum help in building cell membranes.

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