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In DNA and RNA, nitrogen atom is present in the ring system. Can Kjeldahl method be used for the estimation of nitrogen present in these? Give reasons.

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In the case of DNA and RNA, nitrogen is present in the heterocyclic base and in the ring not as a substituent. Therefore, nitrogen present in the ring cannot be converted into(NH_{4} )_{2}SO_{4}. Hence, it cannot be estimated by the Kjeldahl method.

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