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  • Assertion (A): Enzymes have active sites that hold substrate molecule for a chemical reaction.Reason (R): Drugs compete with natural substrate by attaching covalently to the active site of enzyme.

In the following questions, a statement of Assertion (A) followed by a statement of Reason (R) is given. Choose the correct answer out of the following choices:

(i) Assertion and reason both are correct statement but reason does not explain assertion.
(ii) Assertion and reason both are correct and reason explains the assertion.
(iii) Both assertion and reason are wrong statement.
(iv) Assertion is correct statement reason is wrong statement.
(v) Assertion is wrong statement reason is correct statement.

Assertion (A): Enzymes have active sites that hold substrate molecule for a chemical reaction.
Reason (R): Drugs compete with natural substrate by attaching covalently to the active site of enzyme.

 

Answers (1)

(iv) To compete for the binding at the active site of receptors, inhibitor drugs compete with the natural substrate by attaching with bonds like H-bonding, van der Waals interaction, etc.

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Gurleen Kaur

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