14.12 Define the following as related to proteins
i) Peptide linkage
Peptide linkage is an amide bond formed between –COOH group and –NH2 group. The reaction between two molecules of either different or similar amino acids proceeds by the combination of the amino group of one molecule with the carboxyl group of the other molecule. This will result in the elimination of a water molecule and formation of a peptide bond –CO–NH–.
This bond links two consecutive alpha-amino acids from C1 (carbon number one) of one alpha-amino acid and N2 (nitrogen number two) of another. This linkage is found along a peptide or protein chain.