Match the class of compounds given in Column I with their functions given in Column II.
The correct match of compounds with their functions is - (i —> b), (ii —> d), (iii —> a), (iv —> e), (v —> c)
(i) Antagonist drugs are used for inhibiting the functioning of specific enzyme receptors. For example, to block the dopamine receptors by receptor antagonism, the drug used is of the dopamine antagonist category.
(ii) Agonist drugs are used and effective only in the absence of a chemical messenger, e.g. heroin
(iii) Chemical messengers are responsible for communicating the message from two neurons and that between neurons to muscles. These compounds are present at the site of binding in receptors.
(iv) The role of inhibitors is to block the binding site of the receptors hence hindering the catalytic activity of the enzymes
(v) Receptors are very significant for the body as these proteins are present in the cell membrane to transmit and communicate with other cells.
(i) Antagonist- (b) binds to the receptor site and inhibit its natural function (eg- Mizolastine for histamin)
(ii) Agonist- (d) Mimic the natural messenger (eg- Carbacol for Acetylcholine)
(iii) Chemical messenger - (a) communicate a message between two neurons and that between neurons to muscles (eg- adrenaline)
(iv) Inhibitors- (e) Inhibits activities of enzymes (eg- cimetidine for cytochrome P450 enzyme)
(v) Receptors -(c) Crucial to body's communication process (e- GABA receptor)
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The correct match of compounds with their functions is - (i —> b), (ii —> d), (iii —> a), (iv —> e), (v —> c)
(i) Antagonist drugs are used for inhibiting the functioning of specific enzyme receptors. For example, to block the dopamine receptors by receptor antagonism, the drug used is of the dopamine antagonist category.
(ii) Agonist drugs are used and effective only in the absence of a chemical messenger, e.g. heroin
(iii) Chemical messengers are responsible for communicating the message from two neurons and that between neurons to muscles. These compounds are present at the site of binding in receptors.
(iv) The role of inhibitors is to block the binding site of the receptors hence hindering the catalytic activity of the enzymes
(v) Receptors are very significant for the body as these proteins are present in the cell membrane to transmit and communicate with other cells.