10.7 Which alkyl halide from the following pairs would you expect to react more rapidly by an mechanism? Explain your answer.
(i) or
In reaction, The nucleophile attacks from the less hindered side or the back side in the transition state of the substrate.
Since 1- Bromobutane is a primary alkyl halide and 2- Bromobutane is a secondary alkyl halide hence primary alkyl halide is less hindered than the secondary and secondary alkyl halide is less hindered than the tertiary alkyl halide so 2- Bromobutane gives more hindrance to the nucleophile.
Hence 1- Bromobutane reacts faster than 2- Bromobutane.