10. Consult internet and find out how to make orally active protein pharmaceutical. What is the major problem to be encountered?
Orally active protein pharmaceuticals contain biologically active proteins, peptides etc. These are taken into the body by oral route in various formulations. The production of these protein pharmaceuticals involves encapsulation of proteins or peptides in liposomes using penetration enhancers. These proteins or peptides are used for the treatment of diseases and they can also be used as vaccines.
The major problem encountered in the administration of these pharmaceuticals is that they are ingested orally, and digested by the proteases present in the stomach before showing results. This is why such pharmaceuticals are directly ingested into the target site.