How does inhibitory gene action occur at the molecular level?
Binding of transcription factors to enhancer regions
Methylation of DNA sequences
Activation of RNA polymerase
Increase in histone acetylation
Inhibitory gene action can occur at the molecular level through DNA methylation, a process that involves the addition of a methyl group to the cytosine nucleotides in the DNA molecule. This methylation modifies the structure of DNA, making it less accessible to transcription factors and other proteins necessary for gene expression. As a result, the target gene is inhibited or silenced, preventing it from being expressed.
Methylation of DNA is a stable and heritable epigenetic modification that can be passed on to daughter cells during cell division. It is an essential mechanism for regulating gene expression and maintaining cell identity and function. Methylation patterns can be influenced by various factors, such as environmental stimuli, age, and disease, and can have significant implications for development, health, and disease susceptibility.
Option b is the correct answer.