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Get Answers to all your Questions
- #Genetics and Evolution
- #National Eligibility Cum Entrance Test - 2023
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Unequivocal proof that DNA is the genetic material was first proposed by
Frederic Griffith
Alfred Hershey and Martha Chase
Avery, Macleoid and McCarthy
Wilkins and Franklin
Answers (1)
The correct option is Option 2) Alfred Hershey and Martha Chase.
Alfred Hershey and Martha Chase conducted the Hershey-Chase experiment in 1952, which provided unequivocal proof that DNA is the genetic material. In their experiment, they used bacteriophages, which are viruses that infect bacteria. They labeled the DNA of the bacteriophage with radioactive phosphorus-32 and the protein coat with radioactive sulfur-35.
By infecting bacteria with these labeled bacteriophages and then separating the viral DNA and proteins from the infected bacteria, Hershey and Chase showed that only the radioactive DNA, not the protein, was transferred to the next generation of phages. This demonstrated that DNA, not protein, carried the genetic information and served as the hereditary material.
Their experiment provided strong evidence supporting the idea that DNA, rather than protein, is the genetic material responsible for the transmission of inherited traits. Therefore, Hershey and Chase were the ones who first proposed the unequivocal proof that DNA is the genetic material.
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