Transition state structure of the substrate formed during an enzymatic reaction is:
permanent and stable
transient but stable
permanent but unstable
transient and unstable
As discussed in
Nature of Enzyme Action -
Each Enzyme (E) has a subtract (S) binding to the molecule so that a highly reactive enzyme substrate complex (ES) is produced, which is short-lived and dissociates into its product and unchanged Enzyme
- wherein
The formation of ES complex is essential for catalysts.
Enzyme substrate complex is short lived, hence unstable and transient.
Option 1)
permanent and stable
Option is incorrect
Option 2)
transient but stable
Option is incorrect
Option 3)
permanent but unstable
Option is incorrect
Option 4)
transient and unstable
Option is correct