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Assertion(A): Cyanide exerts its lethal effects on organisms by selectively inhibiting cytochrome oxidase, an indispensable mitochondrial enzyme involved in cellular respiration.
Reason(R): This phenomenon is a clear illustration of non-competitive inhibition.
If both statements A and R are true, and R is the correct explanation of A.
If both statements A and R are true, but R is not the correct explanation of A.
If statement A is true, but statement R is false.
If both statements A and R are false.
Answers (1)
Cyanide is indeed known to inhibit cytochrome oxidase, a crucial enzyme involved in cellular respiration. However, the inhibition caused by cyanide is not classified as non-competitive inhibition. Non-competitive inhibition occurs when the inhibitor binds to a site on the enzyme other than the active site, which does not appear to be the case with cyanide. Therefore, while both statements are true, statement R is not the correct explanation of statement A.
Hence, the correct answer is option 2.
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