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The harmful allele of sickle cell anaemia has not been eliminated from the human population. Such afflicted people derive some other benefit. Discuss.

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Individuals diagnosed with sickle cell anaemia exhibit a reduced vulnerability to malaria, an infectious disease transmitted by mosquitoes. Research indicates that in regions where malaria is prevalent, there is often a correspondingly higher incidence of sickle cell anaemia. This correlation may be attributed to the protective effects that the sickle cell trait provides against the malaria parasite. Essentially, the abnormal haemoglobin found in individuals with sickle cell anaemia can hinder the development of the malaria parasite within their red blood cells, thereby offering a biological advantage in areas where malaria is endemic. Understanding this relationship is crucial for public health strategies aimed at managing both sickle cell anaemia and malaria in affected populations.

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