(a) Explain the process of DNA replication in prokaryotes.
(b) Write the phase in cell cycle where DNA replication occurs in a cell. What will happen if cell division fails to occur after DNA replication in a cell ?

 

 
 
 
 
 

Answers (1)

a) The DNA replication in prokaryotes takes place in the following place:

  • The two strands of DNA unwind at the origin of replication.
  • Then helicase opens the DNA and replication forks are formed.
  • Then DNA is coated by the single-strand binding proteins around the replication fork to prevent rewinding of DNA.
  • Topoisomerase prevents the supercoiling of DNA.
  • RNA primers are synthesised by primase. These primers are complementary to the DNA strand.
  • DNA polymerase III starts adding nucleotides at the end of the primers.
  • The leading and lagging strands continue to elongate.

b) S Phase of Interphase

If cell division fails to occur after DNA replication in a cell cause mutations and chromosome rearrangements, leading to diseases or even can lead to death.

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