(a) Write the scientific name of the organism Griffith used in his experiments. State the conclusions he arrived at.

(b) Name the scientists and describe how they experimentally proved the biochemical nature of the genetic material which was earlier considered as protein.

 

 
 
 
 
 

Answers (1)

A) Streptococcus pneumonia

  • He concluded that the R strain bacteria has been transformed by the heat-killed S strain bacteria.
  • Strain to become virulent from non-virulent.
  • he proved the transforming principle of genetic material.


B) Scientists:

  • (Oswald) Avery    
  • (Colin) MacLeod
  • (Maclyn) McCarty

These scientists purified biochemicals (DNA, RNA, proteins) from the heat-killed S cells to see which ones could transform live R cells Into S cells. They also discovered that protein-digesting enzymes (proteases) and RNA-digesting enzymes (RNases) did not affect transformation, so the transforming substance was not a protein or RNA.

So, digestion with DNase did not inhibit transformation, suggesting that the DNA caused the transformation.

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