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  • Explain the relationship of ribosomest RNA and m RNA during the process of translation in Prokaryotes.

Explain the relationship of ribosomes, t-RNA and m-RNA during the process of translation in Prokaryotes.

 

 

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During the process of translation in prokaryotes, amino acids are activated in the presence of ATP and they are linked to their aminoacylation of tRNA, as ribosome is the cellular factory for protein synthesis which exists as two subunits for the initiation and this small subunit of ribosome binds to mRNA at the start codon that is AUG. Then it is recognised by initiator t-RNA, large subunit has two sites for subsequent amino acids to bind to each other with a peptide bond. Then it proceeds towards the elongation process where charged tRNAs sequentially bind to the appropriate codon in mRNA, by forming complementary base pairs with the tRNA anticodon. Then ribosome moves codon by codon along with the m-RNA, and amino acids are added one by one, at the end, a release factor binds to the stop codon which can be UAA / UAG / UGA for terminating the translation.

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Safeer PP

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