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  • With the help of an algebraic equation, how did Hardy-Weinberg explain that in a given population the frequency of occurrence of alleles of a gene is supposed to remain the same through generations ?   

With the help of an algebraic equation, how did Hardy-Weinberg explain that in a given population the frequency of occurrence of alleles of a gene is supposed to remain the same through generations ? 

 

 

 

 
 
 
 
 

Answers (1)

Hardy Weinberg principle says that allele frequencies in a population are stable and is constant from generation to generation. The gene pool (total genes and their alleles in a population) remains a constant. This is called genetic equilibrium. Sum total of all the allelic frequencies is 1. Individual frequencies, for example, can be named p, q, etc. In a diploid, p and q represent the frequency of allele A and allele a. The frequency of AA individuals in a population is simply p2. This is simply stated in another ways, i.e., the probability that an allele A with a frequency of p appear on both the chromosomes of a diploid individual is simply the product of the probabilities, i.e., p2. Similarly of aa is q2, of Aa 2pq. Hence, p^{2}+2pq+q^{2}=1. This is a binomial expansion of (p+q)2.

When frequency measured, differs from expected values, the difference (direction) indicates the extent of evolutionary change. Disturbance in genetic equilibrium, or Hardy- Weinberg equilibrium, i.e., change of frequency of alleles in a population would then be interpreted as resulting in the evolution.

Posted by

Priyanka Kumari

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