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If a person is suffering from the deficiency if nor-adrenaline, what kind of drug can be suggested ?  
Option: 1 Anti-inflammatory
Option: 2 Antidepressant
Option: 3 Antihistamine
Option: 4 Analgesic

Non-adrenaline is a neurotransmitter. If nor-adrenaline is low, a person may suffer from depression. Hence, an antidepressant drug is suggested.

Anti-depressant → drug, which enhances the mood.

Therefore, the correct option is (2).

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Posted by

Kuldeep Maurya

The following molecules act as an :
Option: 1 Antidepranant
Option: 2 Anti-bacterial  
Option: 3 Antiseptic
Option: 4 Anti-histamine

Brompheniramine works by blocking the action of histamine, which causes allergic symptoms.

Hence, it acts as an antihistamine.

Therefore, Option(3) is correct.

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Posted by

Kuldeep Maurya

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The mechanism of action of "Terfenadine'' (Seldane) is:
Option: 1 Activates the histamine receptor
Option: 2 Inhibits the secretion of histamine
Option: 3 helps in the secretion of histamine
Option: 4 inhibits the action of histamine receptor

Seldane is an antihistamine drug.

The mechanism of action of “Terfenadine” (Seldane) is to inhibit the action of histamine receptor.

Therefore, the correct option is (4).

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Posted by

Kuldeep Maurya

The antifertility drug "Novestrol" can react with
Option: 1 \mathrm{ZnCl _{2} / HCl ; FeCl _{3} \text { Alocholic } HCN}
Option: 2 \mathrm{Br _{2} / \text { water; } ZnCl _{2} / HCl ; FeCl _{3}}
Option: 3 \mathrm{\text { Alcoholic } HCN ; NaOCl ; ZnCl _{2} / HCl}
Option: 4 \mathrm{Br _{2} / \text { water } ; ZnCl _{2} / HCl ; NaOCl}

Alkyne group will react with \mathrm{Br _{2} \text { water }}

Tertiary alcohol will react with \mathrm{ZnCl _{2} / HCl}

Phenolic group will react with \mathrm{FeCl _{3}}

Therefore, Option(2) is correct.

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Kuldeep Maurya

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Match the following drugs with their therapeutic actions : (i) Ranitidine                                      (a) Antidepressant (ii) Nardil(Phenelzine)                        (b) Antibiotic (iii) Chloramphenicol                         (c) Antihistamine (iv) Dimethane(Brompheniramine)   (d) Antacid                                                                   (e) Analgesic
Option: 1 (i)-(a); (ii)-(c); (iii)-(b); (iv)-(e)
Option: 2 (i)-(d); (ii)-(a); (iii)-(b); (iv)-(c)
Option: 3 (i)-(e); (ii)-(a); (iii)-(c); (iv)-(d)
Option: 4 (i)-(d); (ii)-(c); (iii)-(a); (iv)-(e)

Drugs with their therapeutic actions :

Ranitidine \rightarrow Antacid
Nardil (Phenelzine)\rightarrow Antidepressant
Chloramphenicol \rightarrow Antibiotic
Dimethane (Brompheniramine) \rightarrow Antihistamine

Therefore, Option 2 is correct.

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Posted by

Kuldeep Maurya

Match List - I with List - II
List - I List - II
(Class of Drug) (Example)
(a) Antacid (i) Novestrol
(b) Artificial Sweetener (ii) Cimetidine
(c) Antifertility (iii) Valium
(d) Tranquilizers (iv) Alitame
Choose the most appropriate match :
 
Option: 1 (a) - (ii), (b) - (iv), (c) - (iii), (d) - (i)
Option: 2 (a) - (iv), (b) - (i), (c) - (ii), (d) - (iii)
Option: 3 (a) - (ii), (b) - (iv), (c) - (i), (d) - (iii)  
Option: 4 (a) - (iv), (b) - (iii), (c) - (i), (d) - (ii)

We know these facts about drugs.

(a) Antacid: Cimetidine
(b) Artificial Sweetener : Alitame
(c) Antifertility : Novestrol
(d) Tranquilizers: Valium

So, the correct match:  (a)-(ii), (b)-(iv), (c)-(i), (d)-(iii)

Therefore, the Correct option is (3)

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Kuldeep Maurya

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Match the List -I with List -II
List - I (Class of Chemicals) List - II (Example)
a. Antifertility drug i. Meprobamate
b. Antibiotic ii. Alitame
c. Tranquilizer iii. Norethindrome
d. Artificial Sweetener iv. Salvarsan
Choose the correct option.
Option: 1 a-iii, b-iv, c-i, d-ii
Option: 2 a-ii, b-iii, c-iv, d-i
Option: 3 a-iv, b-iii, c-ii, d-i
Option: 4 a-ii, b-iv, c-i. d-iii

We know,

(a) Antifertility drug  -------  Norethindrone
(b) Antibiotic  -------  Salvarsan
(c) Tranquilizer  -------  Meprobamate
(d) Artificial sweetener  -------  Alitame

So, the correct match-

(a)-(iii), (b)-(iv), (c)-(i), (d)-(ii)

Therefore, the Correct option is (1)

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Kuldeep Maurya

With respect to drug-enzyme interaction, identify the wrong statement.
Option: 1 Allosteric inhibitor competes with the enzyme's active site
Option: 2 Non-Competitive inhibitor binds to the allosteric site
Option: 3 Competitive inhibitor binds to the enzyme's active site
Option: 4 Allosteric inhibitor changes the enzyme's active site

Drugs compete with the natural substrate for their attachment on the active sites of enzymes. Such drugs are called competitive inhibitors.

Some drugs do not bind to the enzyme’s active site. These bind to a different site of enzyme which is called allosteric site.

This binding of inhibitor at allosteric site  changes the shape of the active site in such a way that substrate cannot recognise it.

From above concept- Correct statement are-

2) Non-Competitive inhibitor binds to the allosteric site.

3) Competitive inhibitor binds to the enzyme's active site

4) Allosteric inhibitor changes the enzyme's active site.

So, incorrect will be -

1) Allosteric inhibitor competes with the enzyme's active site

Therefore, Correct option is (1)

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Kuldeep Maurya

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The functions of antihistamine are :
Option: 1 Antiallergic and Analgesic
Option: 2 Antiallergic and antidepressant
Option: 3 Antacid and antiallergic
Option: 4 Analgesic and antacid

The functions of Antihistamines are Antacid and Anti-allergic.

Hence, the correct answer is Option (3)

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Kuldeep Maurya

Which one of the following chemicals is responsible for the production of \mathrm{HCl}  in the stomach leading to irritation and pain?
Option: 1
Option: 2
Option: 3
Option: 4

Histamine is responsible for production of \mathrm{HCl} in the stomach leading to irritation and pain.

Its structure is given as:

Hence the correct answer is option (3)

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Posted by

sudhir.kumar

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