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Assertion (A): Integration into the host cell's chromosome is a common outcome for plasmids used as cloning vectors following transformation.
Reason (R): Plasmids undergo fragmentation or disintegration upon transformation.
Both Assertion (A) and Reason (R) are true, and Reason (R) is the correct explanation of Assertion (A).
Both Assertion (A) and Reason (R) are true, but Reason (R) is not the correct explanation of Assertion (A).
Assertion (A) is true, but Reason (R) is false.
Both Assertion (A) and Reason (R) are false.
Answers (1)
Assertion (A) claims that plasmids as cloning vectors usually integrate into the host cell's chromosome after transformation. However, this statement is not true. Plasmids used as cloning vectors typically remain as separate, extrachromosomal entities within the host cell and do not integrate into the chromosome unless specific mechanisms or techniques are employed to facilitate integration.
However, Reason (R) is false in suggesting that plasmids get disintegrated after transformation. Plasmids typically do not disintegrate or fragment upon transformation. Instead, they persist as separate, extrachromosomal elements within the host cell, unless they undergo integration into the chromosome. Therefore, the correct answer is option 4 - Both Assertion (A) and Reason (R) are false.
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