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Barr bodies are found
Option: 1
In the cytoplasm of female
Option: 2
In the cytoplasm of male
Option: 3
In the nuclei of female
Option: 4
In the nuclei of male
Answers (1)
As we have studied in:
Dosage Compensation, Barr Body & Lyon Hypothesis -
- In man it has been found that Y-chromosomes are genetically inert in comparison to the X-chromosomes and other chromosomes and only a few genes are present in the human Y-chromosome.
- As per the chromosomal make-up of human male and female, females contain a higher dose of functional gene containing chromosome than males (Female chromosome numbers = 44 + XX and Male chromosome number = 44 + XY).
- The geneticists have observed that in some cases, female homozygous for the genes in the X-chromosomes do not express a trait more markedly than do hemizygous males.
- So, it must be a mechanism of “dosage compensation”, through which the effective dosage of genes of the two sexes is made equal or nearly so.
- This mechanism of compensating the differential doses of functional sex chromosomes in male and female human is effected by the inactivation of one X-chromosome in the normal female.
- The genetically inactive X- chromosome or condensed X-chromosome is called heterochromatin or sex-chromatin body or Barr body.
The inactivated X chromosome in female forms a highly condensed structure called the Barr body which is found in the nuclei. As male has only one X chromosome is no inactivation and no Barr body.
Hence, the correct answer is option c.
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