Convesion of glucose to glucose - 6 - phosphate, the first irrevesible reaction of glycolysis, is catalysed by:
The answer to this question is hexokinase.
option 2) Hexokinase
During glycolysis, glucose is phosphorlayted by a family of enzymes called hexokinase to form glucose - 6 - phosphate. This reaction required ATP and it is an irrevesible reaction. Hexokinase is a kind of transferase enzymes.