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During DNA replication, Which of the following reactions is required for proofreading by DNA Pol III?
 

Option: 1

 5’ to 3’ exonuclease activity
 


Option: 2

3’ to 5’ exonuclease activity
 


Option: 3

5’ to 3’ endonuclease activity


Option: 4

3’ to 5’ endonuclease activity
 


Answers (1)

 

 

As we have already discussed in DNA Replication in Prokaryotes -

 

DNA Polymerase III shows 3’-5’ exonuclease proofreading activity. It helps in the removal of mispaired nucleotides so that the polymerase begins again. Hence, the correct option is (b).
 

Posted by

Sumit Saini

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