Histone variants play important roles in chromatin function in mammalian cells. Which one of the following statements is correct in the context of the histone variants?
Histone variants have been reported for H3 and H4 but not for H2A and H2B
Histone variants have been reported for H3, H4, H2A but not for H2B
Histone variants have been reported for H3, H4, H2B but not for H2A
Histone variants have been reported for H3, H4, H2A and H2B
Histone variants are proteins that substitute for the core canonical histones (H3, H4, H2A, H2B) in nucleosomes in eukaryotes and often confer specific structural and functional features. Hence, the correct answer is option 4.