Transplantation of tissues/organs fails often due to non-acceptance by the patient's body. Which type of immune-response is responsible for such rejections?

  • Option 1)

    Autoimmune response

  • Option 2)

    Cell-mediated immune response

  • Option 3)

    Hormonal immune response

  • Option 4)

    Physiological immune response

 

Answers (1)

As we learnt

Transplantation -

Very often, when some human organs like heart, eye, liver, kidney fail to function satisfactorily, transplantation is the only remedy to enable the patient to live a normal life

- wherein

For this a suitable donor is required. Grafts from just any source – an animal, another primate, or any human beings cannot be made since the grafts would be rejected sooner or later. Tissue matching, blood group matching are essential before undertaking any graft/transplant and even after this the patient has to take immuno–suppresants all his/her life. The body is able to differentiate ‘self ’ and ‘nonself’ and the cell-mediated immune response is responsible for the graft rejection

 

 Transplantation may be rejected in a patient due to the cell-mediated immune response that is mediated by T-lymphocytes.


Option 1)

Autoimmune response

This solution is incorrect 

Option 2)

Cell-mediated immune response

This solution is correct 

Option 3)

Hormonal immune response

This solution is incorrect 

Option 4)

Physiological immune response

This solution is incorrect 

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