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Get Answers to all your Questions
Calcium is impotanat in skeletal muscle contraction because it
- Option 1)
detaches the myosin head from the actin filament.
- Option 2)
activates the myosin ATPase by binding to it.
- Option 3)
binds to troponin to remove the masking of active sites on actin for myosin.
- Option 4)
prevents the formation of bonds between the myosin cross bridges and the actin filament.
Answers (2)
As we learnt in
Mechanism of Muscle Contraction -
Release of Calcium ions.
- wherein
A neural signal reaching the neuromuscular junction releases a neurotransmitter (Acetyl choline) which generates an action potential in the sarcolemma. This spreads through the muscle fibre and causes the release of calcium ions into the sarcoplasm.
Signal for contraction increase Ca++ level many folds in the sarcoplasm after which Ca++ binds with sub-unit of troponin (troponin "C") which is masking the active site on actin filament and displaces the sub-unit of troponin. Once the active site is exposed, head of the myosin attaches and initiate contraction by sliding the actin over myosin.
Option 1)
detaches the myosin head from the actin filament.
This is incorrect.
Option 2)
activates the myosin ATPase by binding to it.
This is incorrect.
Option 3)
binds to troponin to remove the masking of active sites on actin for myosin.
This is correct.
Option 4)
prevents the formation of bonds between the myosin cross bridges and the actin filament.
This is incorrect.
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