Which statement is wrong for Krebs' cycle?
There are three points in the cycle where NAD+ is reduced to NADH+H+
There is one point in the cycle where FAD+ is reduced to FADH2
During conversion of succinyl CoA to succinic acid, a molecule of GTP is synthesised
The cycle starts with condensation of acetyl group (acetyl CoA) with pyruvic acid to yield citric acid
As discussed in
Kreb's cycle TCA / Citric Acid Cycle -
It operates in the mitochondria matrix. All enzymes of Kreb's cycle is present in matrix but succinate dehydrogenase is present on inner mitochondrial membrane.
2 Acetyl CoA + 6H2O + 6NAD+ + 2FAD + 2GDP + 2Pi 4Co2 + 2H2O + 6NADH + 6H+ + 2FADH2 + 2GTP + 2 Coenzyme A
- wherein
Kreb's cycle starts with the synthesis of citrate by addition of water molecule (hydration).
Option 1)
There are three points in the cycle where NAD+ is reduced to NADH+H+
This option is incorrect.
Option 2)
There is one point in the cycle where FAD+ is reduced to FADH2
This option is incorrect.
Option 3)
During conversion of succinyl CoA to succinic acid, a molecule of GTP is synthesised
This option is incorrect.
Option 4)
The cycle starts with condensation of acetyl group (acetyl CoA) with pyruvic acid to yield citric acid
This option is correct.