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In Drosophila, what is the role of the transformer (Tra) gene?

Option: 1

Promotes male development


Option: 2

 Promotes female development


Option: 3

Determines the number of X chromosomes


Option: 4

 Determines the number of autosomes


Answers (1)

best_answer

The Transformer (Tra) gene in Drosophila is responsible for promoting female development. It is involved in the regulation of sexual differentiation by controlling the splicing of the doublesex (dsx) pre-mRNA transcript. In females, the Tra protein is present, and it interacts with other proteins to promote the splicing of dsx into a female-specific isoform. This isoform then directs the development of female-specific structures and traits.

In contrast, in males, the absence of functional Tra protein results in the alternative splicing of dsx into a male-specific isoform. This male-specific isoform of dsx directs the development of male-specific structures and traits. Therefore, the presence or absence of functional Tra protein is critical in determining the sexual development and differentiation of Drosophila flies.

Option 2 is the correct answer.

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Rishi

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