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In gene regulation, open reading frame (ORF) implies
intervening nucleotide sequence in between two genes.
a series of triplet codons not Interrupted by a stop codon..
a series of triplet codons that begins with a start codon and ends with a stop codon.
the exonic sequence of a gene that corresponds to the 5'UTR of the mRNA and thus does not code for the protein
Answers (1)
In gene regulation, an open reading frame (ORF) refers to a DNA sequence that has the potential to be translated into a protein. It is a continuous series of triplet codons that are not interrupted by a stop codon.
The start codon (usually AUG, which codes for methionine) marks the beginning of an ORF. From the start codon, the ribosome reads the mRNA sequence in a 5' to 3' direction, synthesizing a protein until it reaches a stop codon (UAA, UAG, or UGA), which signals the end of translation.
An ORF is considered to be a potential protein-coding sequence if it contains a start codon followed by a series of triplet codons without any intervening stop codons. This uninterrupted sequence suggests that the reading frame has the potential to be translated into a functional protein.
Hence, the correct answer is option 2.
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