spindle apparatus formation takes place during which stage of cell cycle?
The mitotic cell division is carried out in various stages. Coiling of chromatin material into distinct chromosomes is the most important event of prophase. Formation of spindle apparatus occurs during prometaphase stage. The spindle fibers attach to the centromere.
The nuclear membrane breaks apart into numerous "membrane vesicles", and the chromosomes inside form protein structures called kinetochores. Kinetochore microtubules emerging from the centrosomes at the poles of the spindle reach the chromosomes and attach to the kinetochores, throwing the chromosomes into agitated motion. Other spindle microtubules make contact with microtubules coming from the opposite pole.
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The mitotic cell division is carried out in various stages. Coiling of chromatin material into distinct chromosomes is the most important event of prophase. Formation of spindle apparatus occurs during prometaphase stage. The spindle fibers attach to the centromere.
The nuclear membrane breaks apart into numerous "membrane vesicles", and the chromosomes inside form protein structures called kinetochores. Kinetochore microtubules emerging from the centrosomes at the poles of the spindle reach the chromosomes and attach to the kinetochores, throwing the chromosomes into agitated motion. Other spindle microtubules make contact with microtubules coming from the opposite pole.