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  • The quantitative parameters of DNA replication in E.coli and humans are given below:

The quantitative parameters of DNA replication in E.coli and humans are given below:

  Quantitative parameter E.coli Human
a. DNA content, number of nucleotide pairs per cell 3.9\times10^{6} about 10^{9}
b. Rate of replication fork progression per replication fork (per sec.) \sim 100 \sim 1000
c. Number of replication origins per cell 1 10^{3}-10^{4}
d. Time required for complete genome replication \mathrm{\sim 8\; hrs} \mathrm{\sim 42\; min}

Select the combination which represents all correct parameters.

Option: 1

a,b,c and d


Option: 2

a and b only


Option: 3

b and d only


Option: 4

a and c only


Answers (1)

best_answer

Rate of replication fork progression per replication fork (per sec.) is ~1000 in E.coli and ~100 in Humans. Time required for complete genome replication

is ~42 min. in E.coli and ~8 hrs in Humans.

Therefore a and c are correct. Hence, the correct answer is option 4. 

 

Posted by

Ajit Kumar Dubey

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