The quantitative parameters of DNA replication in E.coli and humans are given below:
Quantitative parameter | E.coli | Human | |
a. | DNA content, number of nucleotide pairs per cell | about |
|
b. | Rate of replication fork progression per replication fork (per sec.) | ||
c. | Number of replication origins per cell | ||
d. | Time required for complete genome replication |
Select the combination which represents all correct parameters.
a,b,c and d
a and b only
b and d only
a and c only
Rate of replication fork progression per replication fork (per sec.) is ~1000 in E.coli and ~100 in Humans. Time required for complete genome replication
is ~42 min. in E.coli and ~8 hrs in Humans.
Therefore a and c are correct. Hence, the correct answer is option 4.