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  • The synthesis of okazaki fragments is a key element in E.coli DNA replication. Each okazaki fragment is initiated by an RNA primer.  Select the correct statement given below:<div class='qn

The synthesis of okazaki fragments is a key element in E.coli DNA replication. Each okazaki fragment is initiated by an RNA primer.  Select the correct statement given below:

Option: 1

The RNA primer is made complementary to the DNA template strand in the direction by an enzyme called DNA Pol. I.


Option: 2

After an Okazaki fragment has been synthesised by the DNA Pol IIl complex, the RNA primer is removed by the 5' to 3' exonuclease activity of DNA Pol I.


Option: 3

The gap that results is filled by DNA Pol I using the 5' end of the Okazaki fragment.

 


Option: 4

Okazaki fragments are covalently joined into one continuous lagging strand by the action of DNA helicase.


Answers (1)

best_answer

The RNA primer is made complementary to the DNA template strand in the direction by an enzyme called primase. The gap that results is filled by DNA Pol I using the 3' end of the Okazaki fragment. Okazaki fragments are covalently joined into one continuous lagging strand by the action of DNA ligase.

Therefore only the 2nd  statement is correct. Hence, the correct answer is option 2. 

Posted by

seema garhwal

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