The experimental proof for semiconservative replication of DNA was first shown in a
As we learnt in
Observations of experiments done by meselsons and stahl -
The DNA that was extracted from the culture of E.coli bacteria one generation after the transfer from 15 N to 14 N medium had a hybrid or intermediate density or DNA extracted another generation (40 minutes) was composed of an equal amount of this hybrid DNA
Semi-conservative DNA replication was first shown in Bacterium Escherichia coli by Matthew Meselson and Franklin Stahl.