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Which of the following statements is true regarding the Lyon Hypothesis?
The Lyon Hypothesis explains the formation of Barr Bodies.
The Lyon Hypothesis explains how dosage compensation occurs in males.
The Lyon Hypothesis proposes random X chromosome inactivation in females.
The Lyon Hypothesis explains the formation of Y chromosomes.
Answers (1)
According to Mary Lyon's Lyon Hypothesis, one of the two X chromosomes is randomly inactivated in each cell during early embryonic development in female mammals. This procedure ensures that the dosage of X-linked genes in males and females is equal. Option c is hence the proper statement. Option an is inaccurate because it refers to the creation of Barr Bodies as a result of the Lyon Hypothesis. Option b is wrong since it pertains to dose compensation in males, which the Lyon Hypothesis does not govern. Option d is erroneous because the Lyon Hypothesis does not explain how Y chromosomes are formed.
Option 3 is the correct answer.
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