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Q8. Briefly mention the mechanism of action of FSH.
Answers (1)
Follicle-stimulating hormone (FSH) is a glycoprotein polypeptide hormone. It is insoluble in lipid and hence cannot enter the target cell. This hormone binds to the cell surface and activates cellular systems to perform functions.
Steps in action of FSH:
- A molecule of FSH binds on the receptor protein present on the cell surface and forms the hormone-receptor complex.
- Formation of hormone-receptor complex activates the enzyme adenyl cyclase.
- Adenyl cyclase converts ATP into cyclic AMP (cAMP) as a second messenger.
- cAMP activates the follicular cells of membrane granulose to secrete estrogens.
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