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  • Formation of the enzyme-substrate complex (ES) is the first step in catalysed reactions. Describe the other steps until the formation of the product.

Formation of the enzyme-substrate complex (ES) is the first step in catalysed reactions. Describe the other steps until the formation of the product.

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Solution:
The first step in catalysed reactions is the formation of the enzyme-substrate complex (ES). The further steps are described below:

1. As described above, in the first step, the substrate binds at the active site which, in turn, results in the formation of the enzyme-substrate complex.
2. The second stage is the transient stage which is the altered structure state. In the absence of enzymes, the activation energy required would have been higher.       But as the enzyme is present, the reaction takes place even with less amount of energy.
3. In the final stage, which is the product formation stage, the product is formed, and the system’s potential energy reduces drastically. Then the enzyme is free to bind with other substrates.

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