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  • What are the changes in the oogonia during the transition of a primary follicle to Graafian follicle?

What are the changes in the oogonia during the transition of a primary follicle to Graafian follicle?

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Following changes occur in the oogonia during the transition of a primary follicle to Graafian follicle:

(a)    Each primary oocyte is surrounded by a layer of granulosa cells; called a primary follicle

(b)    Primary follicle transforms into secondary follicle by getting surrounded by another layer of granulosa cells and a new theca.

(c)    The secondary follicle then transforms into the tertiary follicle. The tertiary follicle is characterised by a fluid-filled cavity called the antrum. At this stage, the         primary oocyte undergoes second meiotic division and forms secondary oocyte and a tiny polar body.

(d)    The tertiary follicle then changes into mature Graafian follicle. During this stage, a new layer; called zona pellucida; develops around the secondary         oocyte.

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