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In Aves, forelimbs are modified into wings for flight. In mammals, the forelimbs are variously adapted for walking, running, climbing, swimming, etc.
Aves have pneumatic bones which are absent in mammals.
Birds excrete uric acid whereas mammals excrete urea.
Mammals show mammary glands which are absent in aves.
Aves are oviparous whereas mammals are viviparous.