14. What is a centromere? How does the position of the centromere form the basis of the classification of chromosomes? Support your answer with a diagram showing the position of the centromere on different types of chromosomes.
A centromere refers to a non-stainable area that attaches two chromatids of a chromosome. Chromosomes are divided into four types based on the position of the centromere can be of the following types:
1. Acrocentric chromosomes
Centromere is present in sub-terminal regions, and chromatids are arranged in J-shaped. One arm is extremely long and the other is extremely short.
2. Metacentric chromosome
Centromere is present in the centre and the chromosome appears V-shaped.
3. Sub-metacentric chromosome
The position of the centromere is sub-median. It appears L-shaped. One arm is slightly longer than the other.
4. Telocentric chromosome
The centromere is terminally placed. Chromosome appears I-shaped.