11. What is oxidative phosphorylation?
Oxidative phosphorylation
Oxidative phosphorylation is the synthesis of energy-rich ATP molecules with the help of energy liberated during oxidation of reduced coenzymes ( NADH and FADH2 ) produced in respiration. The enzyme required for the synthesis is called ATP synthase. It is the fifth complex of ETS. During this process, several oxidation-reduction reactions occur and lead to the generation of a proton gradient. The enzyme ATP synthase (complex V) consists of components. The Fl headpiece is a peripheral membrane protein complex and contains the site for ATP synthesis from ADP and inorganic phosphate whereas the component is a part of the membrane protein complex, which acts as a channel for the crossing of the protons from the inner mitochondrial membrane to the mitochondrial matrix. For every two protons passing through the complex, the synthesis of one ATP molecule takes place.